OK, so today I got this error detailed on this EMEA SBS Team blogpost
It turns out however that my problem was not what the EMEA team were reporting, my issue was that my Dell OEM preinstalled SBS2008 server had a FAT32 Partition on it that looked like this:
The fix for me was to convert the FAT32 drive to NTFS using the convert d: /fs:ntfs command.
I believe that the SBS documentation / support team are writing up some documentation on this right now
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